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Biohacking Supplements

One preparation, one daily dose, whatever you take it for.

$250per 30-day protocol · two 30 ml applicators · $199 on a one-year subscription · free DHL from three applicators

The stable metabolites of the 3-million-year-old Bacillus F organism, cold-processed into precise daily drops for cellular resilience and antioxidant defense.

Best for: NMN-experienced longevity buyers, biohackers tracking biomarkers, professionals 35–65.
  • Postbiotic, no live bacteria
  • 2 ml daily · two presses · sublingual
  • Two 30 ml applicators per 30-day protocol
  • Freezer unopened, fridge once open
  • Nothing to prepare
  • Patent WO2012060729
Bacillus F sublingual applicator pen lying on slate beside a cube of glacial ice and a row of four water droplets. The longevity postbiotic supplement by Bacillus F OÜ, Tallinn, Estonia.
Key takeaways
  • Biohacking Supplements: For the N-of-1 experimenter tracking real biomarkers.
  • A postbiotic: the stable metabolites, not live bacteria. Same on day one as on day thirty.
  • Derived from the Bacillus F strain, patented as WO2012060729 with five national patents.
  • Liquid drops: 2 ml daily (two 1 ml presses), sublingual, two 30 ml applicators per 30-day protocol.
  • Sits alongside NMN and spermidine rather than replacing them. It works on oxidative-stress defense, a different mechanism.

About the formulation

For the n-of-1 experimenter, someone running a protocol on themselves with real measurement attached. This page is less about the product than about how to test it properly, because a badly designed self-experiment turns noise into confident conclusions.

Biohacking has a method problem. The typical protocol changes four things at once, runs for three weeks, and concludes from how someone felt on a Tuesday. That isn't evidence. It is an anecdote with a spreadsheet.

If you're going to run this, run it so it could actually tell you something, including that it did nothing.

How it works

Get a real baseline first. One reading isn't a baseline. Biological-age and oxidative-stress panels carry meaningful variance, so two readings before you start tell you what your noise floor looks like.

Change one thing. If you start this alongside a new training block and a sleep protocol, you have learned nothing about any of them.

Run 90 days. This is a cumulative preparation. Three weeks is inside the noise of most panels.

Re-test under matched conditions: same lab, same assay, same time of day, similar fasting and training state. Half of all dramatic self-experiment results are drift in the measurement, not a change in the person.

Write your prediction down before you start. It is the only defence against reading what you hoped for out of an ambiguous number.

One more thing, because it is the step most people skip. Decide in advance what result would make you stop taking it. If no number would change your behaviour, the experiment is decorative. You aren't testing anything, you are buying reassurance and calling it data. Writing the stopping condition down before the first applicator is what separates an n-of-1 from a subscription.

Specifications

FormatSublingual applicator pen, clear cartridge with measured-dose tip
Active fractionCell-free Bacillus F metabolite complex (postbiotic)
Daily dose2 ml (two 1 ml presses), sublingual, morning
Protocol length30 days per protocol (two applicators) · 90 days recommended before re-testing
StorageFreezer until opened, fridge once open
OriginFermented & bottled in the EU · strain from Yakutia permafrost
DocumentationPatent WO2012060729 · deposited genome sequence
Suggested trial length90 days between matched panels, single-variable
Bacillus F sublingual applicator pen standing on a white laboratory bench beside a glass petri dish, with a microscope and a rack of test tubes softly out of focus behind it. longevity postbiotic supplement by Bacillus F OÜ, Tallinn, Estonia.
Two Bacillus F sublingual applicator pens standing upright in a refrigerator door shelf next to a bottle of milk and a jar of olives — the open-applicator storage the protocol asks for. longevity postbiotic supplement by Bacillus F OÜ, Tallinn, Estonia.

Compliance & standards

The strain and its applications are covered by international patent WO2012060729 plus five national patents, and the organism is sequenced and deposited, so every batch comes from the same defined organism. The patent scans and the comet-assay imaging are published openly on the Science page.

Marketed as a dietary supplement, not a medicine. Statements have not been evaluated by the FDA.

What to expect

Expect the discipline to matter more than the compound. A well-run trial of a mediocre input teaches you more than a sloppy trial of an excellent one.

And expect that a properly designed, single-variable ninety days might come back with nothing. That is a real result and worth knowing. We would rather sell one protocol to someone who measured honestly than twelve to someone who never found out either way.

Use cases

  • Quarterly panel runners with a measurement cadence to slot this into.
  • Stack auditors removing compounds one at a time to find out which were doing anything.
  • Documentation-first experimenters who want the patents and the assay method before the applicator.

Not sure where it fits? Start with Bacillus F vs NMN, our most-read comparison.

Available in your country
Postbiotic drops · United StatesPostbiotic drops · United KingdomPostbiotic drops · CanadaPostbiotic drops · JapanPostbiotic drops · GermanyPostbiotic drops · FrancePostbiotic drops · SpainPostbiotic drops · EU-wide

Frequently asked

Probiotics are live organisms that have to survive digestion and settle in the gut. A postbiotic skips that: you take the finished metabolites, so the dose is consistent and nothing has to stay alive. Same organism, far more predictable.

Yes. Bacillus F works on oxidative-stress defense, NMN on NAD+, spermidine on autophagy. Three separate mechanisms. Plenty of customers run all three; the comparison guides in Learn go through it.

How it feels varies from person to person, so judge it by numbers. Take a baseline biological-age or oxidative-stress panel, run 90 days, re-test. The protocol is built around that rhythm.

The fermentation runs are small and every batch has to pass before it is released. Monthly capacity is capped, so we confirm availability for your country before charging anything.

Support
Immune & Energy Support
Daily immune resilience and steady energy. The same drops, taken for defense.
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Flagship
Postbiotic Supplement
The core Bacillus F formulation: stable metabolites in daily drops.
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Category
Longevity Supplements
Healthy-aging support built on a 3M-year-old organism.
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Limited monthly batches. We confirm availability for your country within 48 hours.

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